研究・活動

誌上発表

1.Unsaturated fatty acids show clear elicitaiton responses in a modified local lymph node assay with an elicitation phase, and positive in the direct peptide reacitivity assay

The Journal of Toxicological Sciences, 40, 843-853, 2015

2.Further development of LLNA:DAE method as stand-alone skin-sensitization testing method and applied for evaluation of relative skin-sensitizing potency between chemicals

The Journal of Toxicological Sciences, 40, 137-150, 2015

3.Development of LLNA:DAE: a new local lymph node assay that includes the elicitation phase,discriminates borderline-positive chemicals, and is useful for cross-sensitization testing

The Journal of Toxicological Sciences, 39, 147-161, 2014

4.A catch-up validation study of an in vitro skin irritation test method using reconstructed human epidermis LabCyte EPI-MODEL24

Journal of Applied Toxicology, 10 Oct, 2013

5.Validation Study of the In Vitro Skin Irritation Test with the LabCyte EPI-MODEL24

Alternatives to Laboratory Animals(ATLA),40, 33-50 , 2012

6.Validation studies on an alternative endpoint for the local lymph node assay(LLNA-DA):Importance of study management

6th WC 429-432 (2008)

7.Interlaboratory validation of the modified murine local lymph node assay based on adenosine triphsphate measurement

Journal of Pharmacological and Toxicological Methods 58 11-26 (2008)

8.皮膚腐食性試験(OECD TG431)での国内市販ヒト三次元培養皮膚モデル「LabCyte EPI-MODEL24」の評価

安研協会報 20号 79-81 (2008)